Ongoing challenges of using immunotherapy in special populations: Poor performance status patients, elderly patients, and people living with HIV.

Immunotherapy with immune checkpoint inhibitors (ICIs) represents a breakthrough in lung cancer treatment. The efficacy of monoclonal antibodies targeting the programmed cell death protein 1 (PD-1), its ligand L1 (PD-L1), and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) pathways has been demonstrated in several randomized trials, resulting in significantly improved survival rates in lung cancer patients, especially those with non-small-cell lung cancer (NSCLC), compared to standard chemotherapy. Hence, new therapeutic options have been opened up for advanced-stage lung cancer patients.

However, most clinical trials on ICIs conducted so far have either excluded patients with poor performance status (PS) or chronic infections like human immunodeficiency virus (HIV), or accrued only a minor proportion of elderly patients despite the lack of an upper age limit. 

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (PE)
MBS6308209-5x02mL 5x0.2mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (APC)
MBS6308200-02mL 0.2mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (APC)
MBS6308200-5x02mL 5x0.2mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (FITC)
MBS6308202-02mL 0.2mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (FITC)
MBS6308202-5x02mL 5x0.2mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (Biotin)
MBS6308201-02mL 0.2mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (Biotin)
MBS6308201-5x02mL 5x0.2mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (Azide free) (HRP)
MBS6308203-02mL 0.2mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (Azide free) (HRP)
MBS6308203-5x02mL 5x0.2mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 405)
MBS6308204-01mL 0.1mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 405)
MBS6308204-5x01mL 5x0.1mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 490)
MBS6308205-01mL 0.1mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 490)
MBS6308205-5x01mL 5x0.1mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 550)
MBS6308206-01mL 0.1mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 550)
MBS6308206-5x01mL 5x0.1mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 650)
MBS6308207-01mL 0.1mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 650)
MBS6308207-5x01mL 5x0.1mL
EUR 4250

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 750)
MBS6308208-01mL 0.1mL
EUR 980

HP, ID (HP, Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain) (MaxLight 750)
MBS6308208-5x01mL 5x0.1mL
EUR 4250

Haptoglobin Human (Haptoglobin Human)
PT_40803
  • Ask for price
  • Ask for price
  • Ask for price
  • 200 µg
  • 1 mg
  • 10 mg

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (AP)
MBS6479474-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (AP)
MBS6479474-5x02mL 5x0.2mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (PE)
MBS6479484-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (PE)
MBS6479484-5x02mL 5x0.2mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (APC)
MBS6479475-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (APC)
MBS6479475-5x02mL 5x0.2mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (Biotin)
MBS6479476-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (Biotin)
MBS6479476-5x02mL 5x0.2mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (FITC)
MBS6479477-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (FITC)
MBS6479477-5x02mL 5x0.2mL
EUR 4250

Hapten/ Hapten-HRP-conjugate stabilizer
DPHHRPG-100mL 100 mL
EUR 59.28

Hapten/ Hapten-HRP-conjugate stabilizer
DPHHRPG-1Liter 1 Liter
EUR 178.6

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (Azide free) (HRP)
MBS6479478-02mL 0.2mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (Azide free) (HRP)
MBS6479478-5x02mL 5x0.2mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 405)
MBS6479479-01mL 0.1mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 405)
MBS6479479-5x01mL 5x0.1mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 490)
MBS6479480-01mL 0.1mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 490)
MBS6479480-5x01mL 5x0.1mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 550)
MBS6479481-01mL 0.1mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 550)
MBS6479481-5x01mL 5x0.1mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 650)
MBS6479482-01mL 0.1mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 650)
MBS6479482-5x01mL 5x0.1mL
EUR 4250

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 750)
MBS6479483-01mL 0.1mL
EUR 980

Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 750)
MBS6479483-5x01mL 5x0.1mL
EUR 4250

Haptoglobin Human Recombinant (Haptoglobin Human)
PT_40804
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 µg
  • 20 µg
  • 1 mg

Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
TA308899 100 µl Ask for price

Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
TA308900 100 µl Ask for price

OPPA01435-200UG - Haptoglobin Human - Human Haptoglobin Protein
OPPA01435-200UG 200ug
EUR 112

Haptamide B
MBS5775214-5mg 5(mg
EUR 915

Haptamide B
MBS5775214-5x5mg 5x5(mg
EUR 3970

Haptamide B
T25488-10mg 10mg Ask for price
Description: Haptamide B

Haptamide B
T25488-1g 1g Ask for price
Description: Haptamide B

Haptamide B
T25488-1mg 1mg Ask for price
Description: Haptamide B

Haptamide B
T25488-50mg 50mg Ask for price
Description: Haptamide B

Haptamide B
T25488-5mg 5mg Ask for price
Description: Haptamide B

Recombinant Haplopelma hainanum Hainantoxin-II.9
MBS1218596-005mgBaculovirus 0.05mg(Baculovirus)
EUR 895

Recombinant Haplopelma hainanum Hainantoxin-II.9
MBS1218596-005mgEColi 0.05mg(E-Coli)
EUR 520

Recombinant Haplopelma hainanum Hainantoxin-II.9
MBS1218596-005mgYeast 0.05mg(Yeast)
EUR 715

Recombinant Haplopelma hainanum Hainantoxin-II.9
MBS1218596-02mgEColi 0.2mg(E-Coli)
EUR 680

Recombinant Haplopelma hainanum Hainantoxin-II.9
MBS1218596-05mgEColi 0.5mg(E-Coli)
EUR 725

Recombinant Haplopelma hainanum Hainantoxin-XI-9
MBS1226898-005mgBaculovirus 0.05mg(Baculovirus)
EUR 910

Recombinant Haplopelma hainanum Hainantoxin-XI-9
MBS1226898-005mgEColi 0.05mg(E-Coli)
EUR 540

Recombinant Haplopelma hainanum Hainantoxin-XI-9
MBS1226898-005mgYeast 0.05mg(Yeast)
EUR 735

Recombinant Haplopelma hainanum Hainantoxin-XI-9
MBS1226898-02mgEColi 0.2mg(E-Coli)
EUR 695

Recombinant Haplopelma hainanum Hainantoxin-XI-9
MBS1226898-05mgEColi 0.5mg(E-Coli)
EUR 760

Recombinant Haplopelma hainanum Hainantoxin-XVI.9
MBS1168887-005mgBaculovirus 0.05mg(Baculovirus)
EUR 900

Recombinant Haplopelma hainanum Hainantoxin-XVI.9
MBS1168887-005mgEColi 0.05mg(E-Coli)
EUR 520

Recombinant Haplopelma hainanum Hainantoxin-XVI.9
MBS1168887-005mgYeast 0.05mg(Yeast)
EUR 720

Recombinant Haplopelma hainanum Hainantoxin-XVI.9
MBS1168887-02mgEColi 0.2mg(E-Coli)
EUR 685

Recombinant Haplopelma hainanum Hainantoxin-XVI.9
MBS1168887-05mgEColi 0.5mg(E-Coli)
EUR 730

Recombinant Haplopelma hainanum Hainantoxin-II-9
MBS1110131-005mgBaculovirus 0.05mg(Baculovirus)
EUR 895

Recombinant Haplopelma hainanum Hainantoxin-II-9
MBS1110131-005mgEColi 0.05mg(E-Coli)
EUR 520

Recombinant Haplopelma hainanum Hainantoxin-II-9
MBS1110131-005mgYeast 0.05mg(Yeast)
EUR 715

Recombinant Haplopelma hainanum Hainantoxin-II-9
MBS1110131-02mgEColi 0.2mg(E-Coli)
EUR 680

Recombinant Haplopelma hainanum Hainantoxin-II-9
MBS1110131-05mgEColi 0.5mg(E-Coli)
EUR 725

Recombinant Haplopelma hainanum Hainantoxin-III-9
MBS1140344-005mgBaculovirus 0.05mg(Baculovirus)
EUR 890

Recombinant Haplopelma hainanum Hainantoxin-III-9
MBS1140344-005mgEColi 0.05mg(E-Coli)
EUR 515

Recombinant Haplopelma hainanum Hainantoxin-III-9
MBS1140344-005mgYeast 0.05mg(Yeast)
EUR 710

Recombinant Haplopelma hainanum Hainantoxin-III-9
MBS1140344-02mgEColi 0.2mg(E-Coli)
EUR 675

Recombinant Haplopelma hainanum Hainantoxin-III-9
MBS1140344-05mgEColi 0.5mg(E-Coli)
EUR 720

Recombinant Haplopelma hainanum Hainantoxin-XVI-9
MBS1085165-005mgBaculovirus 0.05mg(Baculovirus)
EUR 900

Recombinant Haplopelma hainanum Hainantoxin-XVI-9
MBS1085165-005mgEColi 0.05mg(E-Coli)
EUR 520

Recombinant Haplopelma hainanum Hainantoxin-XVI-9
MBS1085165-005mgYeast 0.05mg(Yeast)
EUR 720

Recombinant Haplopelma hainanum Hainantoxin-XVI-9
MBS1085165-02mgEColi 0.2mg(E-Coli)
EUR 685

Recombinant Haplopelma hainanum Hainantoxin-XVI-9
MBS1085165-05mgEColi 0.5mg(E-Coli)
EUR 730

Recombinant Haplopelma hainanum Hainantoxin-VIII.9
MBS1024593-005mgBaculovirus 0.05mg(Baculovirus)
EUR 895

Recombinant Haplopelma hainanum Hainantoxin-VIII.9
MBS1024593-005mgEColi 0.05mg(E-Coli)
EUR 515

Recombinant Haplopelma hainanum Hainantoxin-VIII.9
MBS1024593-005mgYeast 0.05mg(Yeast)
EUR 715

Recombinant Haplopelma hainanum Hainantoxin-VIII.9
MBS1024593-02mgEColi 0.2mg(E-Coli)
EUR 680

Recombinant Haplopelma hainanum Hainantoxin-VIII.9
MBS1024593-05mgEColi 0.5mg(E-Coli)
EUR 725

Recombinant Haplopelma hainanum Hainantoxin-VIII-9
MBS1111091-005mgBaculovirus 0.05mg(Baculovirus)
EUR 895

Recombinant Haplopelma hainanum Hainantoxin-VIII-9
MBS1111091-005mgEColi 0.05mg(E-Coli)
EUR 515

Recombinant Haplopelma hainanum Hainantoxin-VIII-9
MBS1111091-005mgYeast 0.05mg(Yeast)
EUR 715

Recombinant Haplopelma hainanum Hainantoxin-VIII-9
MBS1111091-02mgEColi 0.2mg(E-Coli)
EUR 680

Recombinant Haplopelma hainanum Hainantoxin-VIII-9
MBS1111091-05mgEColi 0.5mg(E-Coli)
EUR 725

Recombinant Haplopelma hainanum Hainantoxin-XIII-9
MBS1250122-005mgBaculovirus 0.05mg(Baculovirus)
EUR 900

Recombinant Haplopelma hainanum Hainantoxin-XIII-9
MBS1250122-005mgEColi 0.05mg(E-Coli)
EUR 525

Recombinant Haplopelma hainanum Hainantoxin-XIII-9
MBS1250122-005mgYeast 0.05mg(Yeast)
EUR 720

Recombinant Haplopelma hainanum Hainantoxin-XIII-9
MBS1250122-02mgEColi 0.2mg(E-Coli)
EUR 685

Recombinant Haplopelma hainanum Hainantoxin-XIII-9
MBS1250122-05mgEColi 0.5mg(E-Coli)
EUR 735

Haptoglobin
AP78677 1mg
EUR 2640

Hp | Haptoglobin
AS10-1312 1 mg
EUR 233

Haptoglobin
AP83683 1mg
EUR 2640

Haptoglobin
AP83875 1mg
EUR 2640

Haptoglobin
AP83959 1mg
EUR 2640

Haptoglobin
AP84082 1mg
EUR 2640

Haptoglobin
AP84671 1mg
EUR 2640

Haptoglobin
E8ET1703-24 100ul
EUR 275
Description: Available in various conjugation types.

Haptoglobin
E8M1510-36 100ul
EUR 275
Description: Available in various conjugation types.

Haptoglobin
E8M1510-37 100ul
EUR 275
Description: Available in various conjugation types.

Haptoglobin
MBS634332-1mg 1mg
EUR 370

Haptoglobin
MBS634332-5x1mg 5x1mg
EUR 1505

Haptoglobin
MBS8534427-01mL 0.1mL
EUR 345

Haptoglobin
MBS8534427-01mLAF405L 0.1mL(AF405L)
EUR 565

Haptoglobin
MBS8534427-01mLAF405S 0.1mL(AF405S)
EUR 565

Haptoglobin
MBS8534427-01mLAF610 0.1mL(AF610)
EUR 565

Haptoglobin
MBS8534427-01mLAF635 0.1mL(AF635)
EUR 565

Haptoglobin
MBS8534644-01mL 0.1mL
EUR 345

Haptoglobin
MBS8534644-01mLAF405L 0.1mL(AF405L)
EUR 565

Haptoglobin
MBS8534644-01mLAF405S 0.1mL(AF405S)
EUR 565

Haptoglobin
MBS8534644-01mLAF610 0.1mL(AF610)
EUR 565

Haptoglobin
MBS8534644-01mLAF635 0.1mL(AF635)
EUR 565

Haptoglobin
MBS8534645-01mL 0.1mL
EUR 345

Haptoglobin
MBS8534645-01mLAF405L 0.1mL(AF405L)
EUR 565

Haptoglobin
MBS8534645-01mLAF405S 0.1mL(AF405S)
EUR 565

Haptoglobin
MBS8534645-01mLAF610 0.1mL(AF610)
EUR 565

Haptoglobin
MBS8534645-01mLAF635 0.1mL(AF635)
EUR 565

Haptoglobin
MBS8534646-01mL 0.1mL
EUR 305

Haptoglobin
MBS8534646-01mLAF405L 0.1mL(AF405L)
EUR 565

Haptoglobin
MBS8534646-01mLAF405S 0.1mL(AF405S)
EUR 565

Haptoglobin
MBS8534646-01mLAF610 0.1mL(AF610)
EUR 565

Haptoglobin
MBS8534646-01mLAF635 0.1mL(AF635)
EUR 565

Haptoglobin (19-347)
pro-1897 2µg
EUR 60
Description: Recombinant Human Haptoglobin (19-347 a.a)

Haptoglobin
pro-567 5µg
EUR 60
Description: Recombinant Human Haptoglobin

pcDNA3.1-HA-PTEN
PPL00065-2a 1212bp
EUR 218
Description: pcDNA3.1(+)

pCDNA3.1-HA-PTEN
PVT20033 2ug
EUR 280

Haptoglobin 5+1
A06632H 2x 25 mL Buffer + 1x 10 mL Ab Ask for price

Haptoglobin 5+1
A06872H 5x 20 mL Buffer + 1x 20 mL Ab Ask for price

Rat Haptoglobin
8110 0.1 mg
EUR 220

Dog Haptoglobin
8120 0.1 mg
EUR 220